Why Groups: They may be placed at the beginning or in the middle of the sentence. If a sentence begins with a why group and is more than 4 words, a comma follows the why group.

Because
So That
Since
To + Action (Verb)

Condition Groups: Condition groups may also be placed in the middle or at the beginning of the sentence. If the condition groups has 4 or more words and is at the beginning of the sentence, a comma is placed after the condition group.

Although
Despite
Even If
Even Though
If
In Spite Of
Regardless
Though
Unless